RPy2和Bioconductor:基因表达实例

时间:2011-08-18 10:20:53

标签: rpy2 bioconductor

我正在尝试使用Rpy2来研究如何使用Rpy2在Bioconductor中进行经典基因表达example,并且我在开始时就卡住了。你如何加载数据?在R中我们做:

> library('ALL')
> library('limma')
> data('ALL')

在Python中我们做:

>>> import rpy2.robjects as robjects
>>> from rpy2.robjects.packages import importr
>>> base = importr('base')
>>> ALL = importr('ALL')

如何做Python的等价物:

> data('ALL') ??

我没有看到在扩展文档中加载包数据的示例。我认为这可能是它,但似乎数据不是正确的类,因为它在signature "character"被提供时featureNames

>>> data = robjects.r('data(ALL)')
>>> data.rclass
<rpy2.rinterface.SexpVector - Python:0x1004b3828 / R:0x10376d558>
>>> featureNames = robjects.r('featureNames')
>>> featureNames(data)
Error in function (classes, fdef, mtable)  : 
  unable to find an inherited method for function "featureNames", for signature "character"
Traceback (most recent call last):
  File "<stdin>", line 1, in <module>
  File "/Library/Python/2.6/site-packages/rpy2-2.2.2dev_20110818-py2.6-macosx-10.6-universal.egg/rpy2/robjects/functions.py", line 82, in __call__
    return super(SignatureTranslatedFunction, self).__call__(*args, **kwargs)
  File "/Library/Python/2.6/site-packages/rpy2-2.2.2dev_20110818-py2.6-macosx-10.6-universal.egg/rpy2/robjects/functions.py", line 34, in __call__
    res = super(Function, self).__call__(*new_args, **new_kwargs)
rpy2.rinterface.RRuntimeError: Error in function (classes, fdef, mtable)  : 
  unable to find an inherited method for function "featureNames", for signature "character"

更新:我想我现在拥有它:

>>> import rpy2.robjects as robjects
>>> from rpy2.robjects.packages import importr
>>> base =  importr('base')
>>> ALL = importr('ALL')
>>> data = robjects.r('data(ALL)')
>>> data.rclass
<rpy2.rinterface.SexpVector - Python:0x258b190 / R:0xdf86c8>
>>> data = robjects.globalenv['ALL']
>>> data
<RS4 - Python:0x2591490 / R:0x29a2134>
>>> data.rclass
<rpy2.rinterface.SexpVector - Python:0x258b3b0 / R:0xdf85c8>
>>> featureNames = robjects.r('featureNames')
>>> featureNames(data)
<StrVector - Python:0x23e4f08 / R:0x304fc00>
['1000..., '1001..., '1002..., ..., 'AFFX..., 'AFFX..., 'AFFX...]
>>> exprs = robjects.r['exprs']
>>> e = exprs(data)
>>> e
<Matrix - Python:0x23b2da0 / R:0x84d8000>
[7.597323, 5.046194, 3.900466, ..., 3.095670, 3.342961, 3.842535]
>>> 

1 个答案:

答案 0 :(得分:2)

这个问题应该在包含bioconductor extensions to rpy2

的Python包中解决