Question

我正在metafor中进行元分析。将森林图从对数比例转换回正常比例后，我希望添加原始的置信区间（在以下数据中以ci.lb和ci.ub指定）。这是因为通过metafor从对数刻度返回的置信区间与原始区间不同，并且我希望我的森林图显示原始的置信区间（由我的Cox比例风险分析输出）

我使用的代码：

library(metafor)
library(tidyverse)

#create data [this is just an example- I have real data]
dat <- tibble(study = c(1, 2, 3, 4, 5, 6),
       yi = runif(6, 0.001, 0.5),
       sei = runif(6, 0.2, 0.4),
       ni = runif(6, 70, 400),
       outcome = "DFS",
       author = "author",
       year = c("2001","2002", "2003","2004", "2005", "2006"),
       ci.lb = runif(6, 0.6, 1.5),
       ci.ub = runif(6, 1.3, 4))

# random-effects model analysis for outcome DFS
res <- rma(yi, sei, ni, data=dat)
res
predict(res, transf=exp, digits=2)

#forest plot
par(mar=c(4,4,1,2))
res <- rma(yi, sei=sei, data=dat, slab=paste(author, year, sep=", "))
tmp <- cumul(res, order=order(dat$year))
forest(tmp, xlim=c(-4,2), at=log(c(0.125, 0.25, 0.5, 1, 2)), 
       atransf=exp, digits=c(2,3), cex=0.75, annotate=FALSE)
par(cex=0.75, font=2)
text(-4, 15, "Author(s) and Year",  pos=4)
text( 2, 15, "Risk Ratio [95% CI]", pos=2)
forest(res, atransf= exp, showweights = T)

有人知道我该怎么做吗？已经为此挣扎了一段时间。非常感谢您提供的任何见解:)谢谢

plot outputted by this code

从对数转换转换回原样后，如何将原始危险比置信区间重新添加到metafor森林图中？

0 个答案: