Question

我有一个简单的数据库，有三种类型的节点（t：转录本，f：蛋白质家族和g：基因。两种类型的关系， PFAM_MRNA （t） - [r] - ＆gt;（f）和父（t） - [p] - ＆gt;（g）。< / p>

    (g:Gene{Name:'g1'})<-[p:Parent]-(t:transcript{Name:'t1'})
    (g:Gene{Name:'g1'})<-[p:Parent]-(t:transcript{Name:'t2'})
    (g:Gene{Name:'g2'})<-[p:Parent]-(t:transcript{Name:'t3'})
    (g:Gene{Name:'g3'})<-[p:Parent]-(t:transcript{Name:'t4'})
    (g:Gene{Name:'g4'})<-[p:Parent]-(t:transcript{Name:'t5'})

    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t1'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t2'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t3'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t4'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t5'})

    (f:PFAM{ID:'PF1040'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t4'})
    (f:PFAM{ID:'PF1040'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t5'})

接下来，我试图将转录本（及其亲本基因）与PF0752连接，但除去也与PF1040相连的转录物（及其亲本基因）。

所以，我的CYPHER查询看起来像是

    MATCH (f)<-[rel:PFAM_MRNA]-(t)-[p:Parent]->(g) 
    WHERE f.ID IN ['PF0752'] 
    AND NOT f.ID IN ['PF1040'] 
    RETURN *

但是，我得到了一个像

的图表

    (g:Gene{Name:'g1'})<-[p:Parent]-(t:transcript{Name:'t1'})
    (g:Gene{Name:'g1'})<-[p:Parent]-(t:transcript{Name:'t2'})
    (g:Gene{Name:'g2'})<-[p:Parent]-(t:transcript{Name:'t3'})
    (g:Gene{Name:'g3'})<-[p:Parent]-(t:transcript{Name:'t4'})
    (g:Gene{Name:'g4'})<-[p:Parent]-(t:transcript{Name:'t5'})

    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t1'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t2'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t3'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t4'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t5'})

而不是

    (g:Gene{Name:'g1'})<-[p:Parent]-(t:transcript{Name:'t1'})
    (g:Gene{Name:'g1'})<-[p:Parent]-(t:transcript{Name:'t2'})
    (g:Gene{Name:'g2'})<-[p:Parent]-(t:transcript{Name:'t3'})

    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t1'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t2'})
    (f:PFAM{ID:'PF0752'})<-[r:PFAM_MRNA]-(t:transcript{Name:'t3'})

非常感谢任何有关如何使其有效的提示/想法。

谢谢，

Answer 1

您可以在模式中添加MATCH (f:PFAM {ID: 'PF0752'}), (pf:PFAM {ID:'PF1040'}) MATCH (f)<-[rel:PFAM_MRNA]-(t)-[p:Parent]->(g) WHERE NOT (pf)<-[:PFAM_MRNA]-(t) RETURN *子句从t到PF1040蛋白：

@total

根据Cypher查询中的传出关系过滤掉节点（类似于SQL外连接）

1 个答案: