将mod_wsgi升级到最新版本后，我的应用程序无法再访问其缓存db（sqlite）。
Apache错误日志显示以下内容：
mod_wsgi (pid=1050): Target WSGI script '/location/to_my_project/project_name/wsgi.py' cannot be loaded as Python module.
mod_wsgi (pid=1050): Exception occurred processing WSGI script '/location/to_my_project/project_name/wsgi.py'.
aceback (most recent call last):
File "/location/to_my_project/project_name/wsgi.py", line 16, in <module>
application = get_wsgi_application()
File "/location/to/my/env/lib/python3.5/site-packages/django/core/wsgi.py", line 14, in get_wsgi_application
return WSGIHandler()
File "/location/to/my/env/lib/python3.5/site-packages/django/core/handlers/wsgi.py", line 153, in __init__
self.load_middleware()
File "/location/to/my/env/lib/python3.5/site-packages/django/core/handlers/base.py", line 80, in load_middleware
middleware = import_string(middleware_path)
File "/location/to/my/env/lib/python3.5/site-packages/django/utils/module_loading.py", line 20, in import_string
module = import_module(module_path)
File "/location/to/my/env/lib/python3.5/importlib/__init__.py", line 126, in import_module
return _bootstrap._gcd_import(name[level:], package, level)
File "<frozen importlib._bootstrap>", line 986, in _gcd_import
File "<frozen importlib._bootstrap>", line 969, in _find_and_load
File "<frozen importlib._bootstrap>", line 958, in _find_and_load_unlocked
File "<frozen importlib._bootstrap>", line 673, in _load_unlocked
File "<frozen importlib._bootstrap_external>", line 665, in exec_module
File "<frozen importlib._bootstrap>", line 222, in _call_with_frames_removed
File "/location/to_my_project/project_name/middleware/some_middleware.py", line 16, in <module>
include_get_headers=True,
File "/location/to/my/env/lib/python3.5/site-packages/requests_cache/core.py", line 182, in install_cache
backend = backends.create_backend(backend, cache_name, backend_options)
File "/location/to/my/env/lib/python3.5/site-packages/requests_cache/backends/__init__.py", line 50, in create_backend
return registry[backend_name](cache_name, **options)
File "/location/to/my/env/lib/python3.5/site-packages/requests_cache/backends/sqlite.py", line 28, in __init__
self.responses = DbPickleDict(location + extension, 'responses', fast_save=fast_save)
File "/location/to/my/env/lib/python3.5/site-packages/requests_cache/backends/storage/dbdict.py", line 58, in __init__
with self.connection() as con:
File "/usr/lib/python3.5/contextlib.py", line 59, in __enter__
return next(self.gen)
File "/location/to/my/env/lib/python3.5/site-packages/requests_cache/backends/storage/dbdict.py", line 70, in connection
con = sqlite.connect(self.filename)
lite3.OperationalError: unable to open database file
运行该进程的用户在发生错误后创建了该文件。使用该用户登录时，我也可以打开/编辑该文件。其他具有相同问题的用户报告说，将文件路径从绝对路径更改为相对路径已经解决了他们的问题，但我一直都是相对的。缓存也在正确的目录中创建。
mod_wsgi版本：4.5.14（之前的版本4.3.0） Django：1.10 Apache：2.4.18 服务器：Ubuntu 16.04
升级wsgi模块后，我没有更改python路径。什么可能是错的任何建议？