加载此程序集将从其他实例生成不同的授权集。 （HRESULT异常：0x80131401）

Question

我们使用Windows更新修补了SharePoint 2013服务器，从那时起我们收到以下错误。我们已重新启动服务器，手动删除了Windows更新，然后重新启动服务器，在Windows更新之前恢复到Windows服务器的副本，但错误仍然存​​在。我们还从Windows目录中删除了临时文件，没有任何帮助。

我附上了一夜之间应用于我们服务器的Windows更新的屏幕截图

 Loading this assembly would produce a different grant set from other     instances. (Exception from HRESULT: 0x80131401) 
Description: An unhandled exception occurred during the execution of the current web request. Please review the stack trace for more information about the error and where it originated in the code. 

Exception Details: System.IO.FileLoadException: Loading this assembly would produce a different grant set from other instances. (Exception from HRESULT: 0x80131401)

Source Error: 

An unhandled exception was generated during the execution of the current web request. Information regarding the origin and location of the exception can be identified using the exception stack trace below.  

Stack Trace: 


[FileLoadException: Loading this assembly would produce a different grant set from other instances. (Exception from HRESULT: 0x80131401)]
System.Linq.Enumerable.Any(IEnumerable`1 source) +0
       System.Web.Compilation.BuildManager.GetPreStartInitMethodsFromAssemblyCollection(IEnumerable`1 assemblies, Boolean buildingFromCache) +210
System.Web.Compilation.BuildManager.CallPreStartInitMethods(String preStartInitListPath, Boolean& isRefAssemblyLoaded) +98
System.Web.Compilation.BuildManager.ExecutePreAppStart() +139
System.Web.Hosting.HostingEnvironment.Initialize(ApplicationManager appManager, IApplicationHost appHost, IConfigMapPathFactory configMapPathFactory, HostingEnvironmentParameters hostingParameters, PolicyLevel policyLevel, Exception appDomainCreationException) +1005

[HttpException (0x80004005): Loading this assembly would produce a different grant set from other instances. (Exception from HRESULT: 0x80131401)]
System.Web.HttpRuntime.FirstRequestInit(HttpContext context) +646
System.Web.HttpRuntime.EnsureFirstRequestInit(HttpContext context) +159
System.Web.HttpRuntime.ProcessRequestNotificationPrivate(IIS7WorkerRequest wr, HttpContext context) +779


--------------------------------------------------------------------------------
Version Information: Microsoft .NET Framework Version:4.0.30319; ASP.NET    Version:4.0.30319.36366 

Answer 1

在Sitecore上进行开发时，我遇到了同样的异常，iisreset消除了这个问题。

Answer 2

解决方案似乎是：

创建一个名为LoaderOptimization的新注册表DWORD值，并在键“HKEY_LOCAL_MACHINE \ SOFTWARE \ Microsoft.NETFramework”中为其赋值1.

进一步阅读：

http://blog.bugrapostaci.com/2017/02/08/loading-this-assembly-would-produce-a-different-grant-set-from-other-instances-exception-from-hresult-0x80131401/

https://social.technet.microsoft.com/Forums/en-US/5db05238-3c12-4e7e-af95-ca56545f0721/loading-this-assembly-would-produce-a-different-grant-set-from-other-instances?forum=sharepointgeneral

Answer 3

我能够通过以下方法解决此问题：进入绑定->编辑，然后删除“ localhost”作为站点的主机名。在那之后工作。

Answer 4

尝试禁用“远程桌面”（如果已启用） （example）

运行命令isreset并更改注册表后，我的问题解决了。

版本信息：Microsoft .NET Framework版本：4.0.30319; ASP.NET版本：4.8.4075.0