我有一台Excel VSTO加载项未在我的某台用户计算机上安装。到目前为止，它安装在其他人的机器上（8台机器），但是在这台特定的机器上，它给出了以下错误消息。
Customization could not be loaded because the application domain could not be created.
************** Exception Text **************
Microsoft.VisualStudio.Tools.Applications.Runtime.CannotCreateCustomizationDomainException: Customization could not be loaded because the application domain could not be created. ---> System.TypeLoadException: Could not load type 'System.AddIn.Pipeline.QualificationDataAttribute' from assembly 'System.AddIn.Contract, Version=2.0.0.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a'.
at System.ModuleHandle.ResolveType(Int32 typeToken, RuntimeTypeHandle* typeInstArgs, Int32 typeInstCount, RuntimeTypeHandle* methodInstArgs, Int32 methodInstCount)
at System.ModuleHandle.ResolveTypeHandle(Int32 typeToken, RuntimeTypeHandle[] typeInstantiationContext, RuntimeTypeHandle[] methodInstantiationContext)
at System.Reflection.Module.ResolveType(Int32 metadataToken, Type[] genericTypeArguments, Type[] genericMethodArguments)
at System.Reflection.CustomAttribute.FilterCustomAttributeRecord(CustomAttributeRecord caRecord, MetadataImport scope, Assembly& lastAptcaOkAssembly, Module decoratedModule, MetadataToken decoratedToken, RuntimeType attributeFilterType, Boolean mustBeInheritable, Object[] attributes, IList derivedAttributes, RuntimeType& attributeType, RuntimeMethodHandle& ctor, Boolean& ctorHasParameters, Boolean& isVarArg)
at System.Reflection.CustomAttribute.GetCustomAttributes(Module decoratedModule, Int32 decoratedMetadataToken, Int32 pcaCount, RuntimeType attributeFilterType, Boolean mustBeInheritable, IList derivedAttributes)
at System.Reflection.CustomAttribute.GetCustomAttributes(RuntimeType type, RuntimeType caType, Boolean inherit)
at System.RuntimeType.GetCustomAttributes(Type attributeType, Boolean inherit)
at System.Runtime.Remoting.Metadata.RemotingCachedData.GetSoapAttribute()
at System.Runtime.Remoting.InternalRemotingServices.GetCachedSoapAttribute(Object reflectionObject)
at System.Runtime.Remoting.SoapServices.GetXmlTypeForInteropType(Type type, String& xmlType, String& xmlTypeNamespace)
at System.Runtime.Remoting.RemotingServices.DetermineDefaultQualifiedTypeName(Type type)
at System.Runtime.Remoting.Metadata.RemotingTypeCachedData.get_QualifiedTypeName()
at System.Runtime.Remoting.Activation.ActivationServices.IsCurrentContextOK(Type serverType, Object[] props, ConstructorCallMessage& ctorCallMsg)
at System.Runtime.Remoting.Activation.ActivationServices.CreateInstance(Type serverType)
at System.Runtime.Remoting.Activation.ActivationServices.IsCurrentContextOK(Type serverType, Object[] props, Boolean bNewObj)
at System.RuntimeMethodHandle._InvokeConstructor(Object[] args, SignatureStruct& signature, IntPtr declaringType)
at System.RuntimeMethodHandle.InvokeConstructor(Object[] args, SignatureStruct signature, RuntimeTypeHandle declaringType)
at System.Reflection.RuntimeConstructorInfo.Invoke(BindingFlags invokeAttr, Binder binder, Object[] parameters, CultureInfo culture)
at Microsoft.VisualStudio.Tools.Office.Runtime.DomainCreator.DomainInitializer.ActivatePipeline(String addInAssembly, String addInClass, String[] pipelineInfo)
at Microsoft.VisualStudio.Tools.Office.Runtime.DomainCreator.DomainInitializer.StartAddIn(IntPtr hostServiceProvider, String[] pipeline, String assemblyName, String[] entryPoints)
at Microsoft.VisualStudio.Tools.Office.Runtime.DomainCreator.DomainInitializer.StartAddIn(IntPtr hostServiceProvider, String[] pipeline, String assemblyName, String[] entryPoints)
at Microsoft.VisualStudio.Tools.Office.Runtime.DomainCreator.LoadMafPipeline(AppDomain newDomain, IntPtr hostServiceProvider, String fullAssemblyName, String[] entryPoints, OfficeApp officeApplication, OfficeVersion officeVersion, IntPtr& executor)
at Microsoft.VisualStudio.Tools.Office.Runtime.DomainCreator.CreateCustomizationDomainInternal(String solutionLocation, String manifestName, String documentName, Boolean showUIDuringDeployment, IntPtr hostServiceProvider, Boolean useFastPath, IntPtr& executor)
--- End of inner exception stack trace ---
************** Loaded Assemblies **************
mscorlib
Assembly Version: 2.0.0.0
Win32 Version: 2.0.50727.5456 (Win7SP1GDR.050727-5400)
CodeBase: file:///C:/Windows/Microsoft.NET/Framework/v2.0.50727/mscorlib.dll
----------------------------------------
Microsoft.VisualStudio.Tools.Office.Runtime.v10.0
Assembly Version: 10.0.0.0
Win32 Version: 10.0.31007.0
CodeBase: file:///C:/Windows/assembly/GAC_MSIL/Microsoft.VisualStudio.Tools.Office.Runtime.v10.0/10.0.0.0__b03f5f7f11d50a3a/Microsoft.VisualStudio.Tools.Office.Runtime.v10.0.dll
----------------------------------------
System
Assembly Version: 2.0.0.0
Win32 Version: 2.0.50727.5456 (Win7SP1GDR.050727-5400)
CodeBase: file:///C:/Windows/assembly/GAC_MSIL/System/2.0.0.0__b77a5c561934e089/System.dll
----------------------------------------
System.Core
Assembly Version: 3.5.0.0
Win32 Version: 3.5.30729.5420 built by: Win7SP1
CodeBase: file:///C:/Windows/assembly/GAC_MSIL/System.Core/3.5.0.0__b77a5c561934e089/System.Core.dll
----------------------------------------
Microsoft.VisualStudio.Tools.Applications.Hosting.v10.0
Assembly Version: 10.0.0.0
Win32 Version: 10.0.31007.0
CodeBase: file:///C:/Windows/assembly/GAC_MSIL/Microsoft.VisualStudio.Tools.Applications.Hosting.v10.0/10.0.0.0__b03f5f7f11d50a3a/Microsoft.VisualStudio.Tools.Applications.Hosting.v10.0.dll
----------------------------------------
System.AddIn
Assembly Version: 3.5.0.0
Win32 Version: 3.5.30729.5446 built by: Win7SP1GDR
CodeBase: file:///C:/Windows/assembly/GAC_MSIL/System.AddIn/3.5.0.0__b77a5c561934e089/System.AddIn.dll
----------------------------------------
Microsoft.VisualStudio.Tools.Applications.ServerDocument.v10.0
Assembly Version: 10.0.0.0
Win32 Version: 10.0.31007.0
CodeBase: file:///C:/Windows/assembly/GAC_MSIL/Microsoft.VisualStudio.Tools.Applications.ServerDocument.v10.0/10.0.0.0__b03f5f7f11d50a3a/Microsoft.VisualStudio.Tools.Applications.ServerDocument.v10.0.dll
----------------------------------------
Microsoft.VisualStudio.Tools.Applications.Runtime.v9.0
Assembly Version: 9.0.0.0
Win32 Version: 9.0.30729.4130
CodeBase: file:///C:/Windows/assembly/GAC_MSIL/Microsoft.VisualStudio.Tools.Applications.Runtime.v9.0/9.0.0.0__b03f5f7f11d50a3a/Microsoft.VisualStudio.Tools.Applications.Runtime.v9.0.dll
----------------------------------------
我不确定为什么会收到此错误。从谷歌搜索，没有任何东西从一个受人尊敬的来源返回。我让用户验证安装了.NET 3.5，以管理员身份运行它，但似乎没有任何帮助。
我有一个安装程序会自动将加载项挂钩到注册表中，但是如果安装了VSTO，则会出现相同的错误消息。
我无法理解此错误消息告诉我的内容。任何人都可以帮助我吗？
答案 0 :(得分：1)
在Windows 7 64位上，我们遇到了类似的问题。一些引用错误是：
Not loaded. A runtime error occurred during the loading of the COM Add-in.
Microsoft.VisualStudio.Tools.Applications.Runtime.CannotCreateCustomizationDomainException: Customization could not be loaded because the application domain could not be created.
System.TypeLoadException: Could not load type 'System.AddIn.Pipeline.QualificationDataAttribute' from assembly 'System.AddIn.Contract, Version=2.0.0.0, Culture=neutral, PublicKeyToken=b03f5f7f11d50a3a'.
此问题是由Microsoft .NET Framework 3.5.1中的损坏引起的，这是操作系统的一项功能。
如何修复或重新安装.NET Framework 3.5 http://www.adminarsenal.com/admin-arsenal-blog/how-to-repair-or-reinstall-net-framework-3-5/
答案 1 :(得分：0)
This post声称在遇到此异常时必须安装完整 .NET框架（而不是客户端配置文件）。有几个人说这解决了他们的问题。
（理想情况下，您的VSTO应该只需要客户端配置文件框架。您在VSTO中是否需要完整框架，或者是先决条件之一？）
答案 2 :(得分：0)
好的 - 事实证明用户机器出了问题。如果用户卸载我的加载项并在其计算机上启用其他加载项，则仍会显示错误消息。是时候解决他的机器而不是我的加载项了！
作为其他人的注释，您可以通过解除将变量添加到环境变量中的错误消息来查看错误消息 - ＆gt;系统变量
变量名称： VSTO_SUPPRESSDISPLAYALERTS
变量值： 0
最终更新：
原来用户有Microsoft Office Professional Plus 2010，而Visual Studio无法为此版本的Microsoft Office生成添加项。